Article · 2 min read

Genioglossus Nerve Stimulation for Sleep Apnea

Genioglossus nerve stimulation is a newer way to treat sleep apnea. Learn how it works and how it compares to Inspire therapy.

General information, not medical advice. Read our disclaimer.

TREATMENT · NERVE STIMULATION

Nerve stimulation at a glance

  • The genioglossus is the biggest muscle in your tongue.
  • A small device under the skin keeps your tongue forward.
  • Inspire is the leading FDA-approved device of this type.
  • Research on newer devices is still going on.
  • A sleep specialist must check whether it is right for you.

Genioglossus nerve stimulation is a new way to treat obstructive sleep apnea. A small device sends mild signals to the nerve that moves your tongue. This keeps your tongue forward so it does not block your airway while you sleep.

What is genioglossus nerve stimulation?

In obstructive sleep apnea, your airway gets blocked again and again while you sleep. The genioglossus is the biggest muscle in your tongue. It helps keep your airway open while you sleep. If this muscle relaxes too much, your tongue falls back. Then it blocks your airway.

How does it work?

A doctor places a small device under your skin. It sends mild electrical signals to the hypoglossal nerve (the nerve that moves your tongue). This nerve controls the genioglossus muscle.

The signals keep your tongue forward while you sleep. This stops it from blocking your airway.

What devices are used today?

Inspire therapy is the best-known device of this kind. It is the leading device of this type approved by the FDA (the U.S. Food and Drug Administration). The FDA has approved it since 2014.

Research on newer devices and methods is still going on. Some work on the nerves on both sides of the tongue. Others place the wires that carry the signal in different ways.

Who may be a good fit?

  • Sleep apnea level — People with moderate to severe obstructive sleep apnea.
  • CPAP trouble — People who cannot use CPAP (a mask that blows air to keep your airway open).
  • Weight — People whose BMI (a measure of weight for height) is in the accepted range.
  • Airway shape — People whose airway shape works well for it. This is checked with DISE, a short test where the doctor looks at your airway while you sleep under medicine.

A sleep specialist must check whether it is right for you.

TREATMENT · HOW IT WORKS

How nerve stimulation keeps your airway open

  1. Device sends signals

    Mild signals go to the hypoglossal nerve, which moves your tongue.

  2. Tongue muscle works

    The nerve controls the genioglossus, your main tongue muscle.

  3. Tongue stays forward

    The signals keep your tongue forward while you sleep.

  4. Airway stays open

    Your tongue no longer falls back and blocks your airway.

    Key point

TREATMENT · WHO IT FITS

Who may be a good fit

Sleep apnea level

What it isModerate to severe obstructive sleep apnea.

Who it helpsPeople whose airway gets blocked again and again.

Good to knowA sleep study shows how severe it is.

CPAP trouble

What it isFor people who cannot use CPAP.

Who it helpsCPAP is a mask that blows air.

Good to knowCPAP is usually tried first.

Weight range

What it isBMI, a measure of weight for height, in the accepted range.

Who it helpsPeople whose BMI meets the rules.

Good to knowYour doctor checks your BMI.

Airway shape

What it isYour airway shape must work well for it.

Who it helpsPeople whose airway closes in a treatable way.

Good to knowChecked with DISE, a short test while sedated.

Common questions

What is genioglossus nerve stimulation?
It is a treatment that uses mild electrical signals to work your main tongue muscle. The signals travel through the hypoglossal nerve (the nerve that moves your tongue). This keeps your airway from closing while you sleep.
How is it different from Inspire?
Inspire is the best-known device that works on this tongue nerve. Other devices that work in a similar way are still being built or tested in studies.

Trusted medical sources

This page follows guidance and research from leading medical organizations.